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Scientists at The Scripps Research Institute (TSRI) have developed a vaccine that blocks the pain-numbing effects of the opioid drugs oxycodone (oxy) and hydrocodone (hydro) in animal models

The gastrointestinal epithelium represents an important interface between the host and the external environment, serving both as a surface for absorption as a defence against ingested pathogens

IGF-1 receptors undergo ligand-induced internalization and degradation when chronically stimulated, reducing cell surface receptor density by 3050% within 34 weeks in myocyte culture models