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GHK-CU is itself a signal peptide, but with the added benefit of copper delivery

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In agreement with the clinical outcomes, markedly lower plasma histamine and IgE levels, augmented IFN-/IL-4 and IL-10/IL-4 ratios, re-methylation of the IL-4 promoter and de-methylation of the IFN- and Foxp3 promoters were observed [39]

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At the same time, the herb exhibits notable neuroactive properties through direct interaction with the GABAergic system, where it is thought to enhance GABAA receptor signaling [49, 50]