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10.1007/s00228-014-1727-5 76 GuptaV.KalraS

Human Evidence To Date Publicly available human data consist of a small 12 patient open label intravesical pilot in women with interstitial cystitis non responsive to prior therapy plus anecdotal or preliminary references to other ongoing studies without published results

Thyroid issues are common, but managing them requires careful attention

Conclusions Iron overload is a pervasive complication in thalassemia syndrome, resulting from repeated transfusions in TDT and excessive iron absorption accompanied by suppressed hepcidin levels in NTDT patients

We hypothesized that a class of drugs known as GLP-1R agonists, which have anti-inflammatory effects and suppress muscle wasting, could be beneficial in this context. To test this, the researchers first determined whether the GLP-1R is expressed on muscle fibers affected in PM by analyzing muscle specimens from patients with PM as well as a mouse model of PM

[DOI] [PubMed] [Google Scholar] 20.Yamada Y, Seino Y