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Nat Metab (2023)

They hold the access to that consumer, so they've begun negotiating for more of the economics away from the card issuers

For example, semaglutide 2.4 mg showed a mean change of -14.9% at 68 weeks vs -2.4% with placebo in one major trial

doi: 10.1111/dom.13078 48 GraigCMLiuL-FDeaconCFHolstJJMcLaughlinTL

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In Denmark, metformin-treated patients with a high household income were more likely to initiate second-line treatment with a GLP-1 RA compared to those with low household income, and this finding was consistent in a subgroup analysis irrespective of presence of cardiovascular disease [16]