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Figure 2 : Pathogenesis of Celiac Sprue (figure from Westerberg et al., 2006 permission pending) Gliadin is absorbed into the lamina propia and presented in conjunction with HLA-DQ2 or DQ8 cell-surface antigens by antigen-presenting cells, probably dendritic cells, to sensitized T cells expressing the / T-cell receptor

The OASIS trial published in the New England Journal of Medicine in 2023 showed oral semaglutide at 50mg produced an average weight reduction of 15.1% over 68 weeks compared to placebo

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10.1016/j.molcel.2012.10.007 74 WongC

Nemati M, Nemati S, Taheri AM, Heidari B