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It's basically what makes us hungry and makes us stop eating when we are full

A phase 1 mechanistic study of people with T2D reported a mean weight change at week 28 of 11.2 kg among participants assigned to tirzepatide 15 mg as compared with 6.9 kg for semaglutide 1.0 mg and no change (0 kg) for placebo [38]

Patients should consult a licensed healthcare provider for personalized recommendations

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As demand increased, several challenges followed

Clinical trials demonstrated a 4.3% BMI reduction over 56 weeks, but gastrointestinal side effects led to treatment discontinuation in some cases