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Tirzepatide (Mounjaro) has shown slightly better weight loss results than semaglutide (Ozempic/Wegovy) in clinical trials

According to the Canadian Adult Obesity Clinical Practice Guidelines , drug therapy for overweight or obesity is indicated only for those with a BMI of 30 kg/m 2 or more, or for those with a BMI of 27 kg/m 2 or more with at least 1 comorbidity

The risk of hypoglycaemia remains low when metformin and GLP-1 receptor agonists are used together without other glucose-lowering medications, as neither typically causes dangerously low blood sugar on their own

Food intake data were expressed as energy intake based on the following conversion: CE-2 3.45 kcal g 1 , HFD-32 5.08 kcal g 1 , and liquid diet 0.644 kcal g 1

Protein rich foods contain all important amino acids like methionine and cysteine

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