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Tirzepatide is the established option with FDA approval, extensive clinical trial data, and growing real-world evidence supporting its efficacy in both type 2 diabetes and obesity

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According to Malhotra, Its always been good practice to treat both the sleep apnea and the obesity in the sense that, if somebody has excess weight, rather than just giving them a CPAP, ideally treat the body weight and the sleep apneanot either/or. GLP-1 use doesnt appear to be causing patients to simply abandon their CPAP, either

For example, if your weekly dose is 6 mg, you would inject 2 mg every two to three days rather than all 6 mg at once

Prior to initiation of treatments, mice were randomized and distributed into groups allowing similar mean values of body weight and fat mass

When these drugs were being developed, researchers observed that rats and mice exposed to high doses of GLP-1 RAs developed an increased incidence of C-cell hyperplasia (an overgrowth of specific thyroid cells) and medullary thyroid tumours