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Individual responses vary widely based on body composition, metabolism, and gastrointestinal sensitivity

The most rapid weight loss phase occurs between weeks 4 and 12 as your body adapts to the medication's appetite-suppressing effects and you maintain consistent lower caloric intake

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If this happens, your PlexusDx provider may increase your dose incrementally or explore dual-compound options like GLP-Squared Injection, which combines semaglutide with tirzepatide to re-engage multiple satiety pathways

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