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The absence of allosteric modulation from the RAMP ECD allows the CTR ECD to adopt a conformation that sits further from the receptor TMD than the position observed in the consensus cryo-EM map
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When youre activating cortisol through a beneficial type of stress the hormetic stressors, like intermittent fasting, like exercise, like deliberate cold exposure its a different biological response
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Cauter, E
The methylation pathway also leads to multiple other pathways (ie
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