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In a case study involving a young woman treated with high doses of cyanocobalamin for pernicious anemia, acne was one of the first symptoms to appear after a total dose of 12 mg of vitamin B12

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Vitamin B12 primarily comes from animal-based products, which makes those who follow vegetarian and vegan diets more likely to develop vitamin deficiency

17 The maintenance of iron homeostasis plays a key role in vital processes such as erythropoiesis, energy metabolism of muscle, cell cycle regulation, hormone production, immune system function, heme synthesis, DNA replication and repair, brain development and aging, and the formation of cytochromes

Iron homeostasis imbalance and ferroptosis in brain diseases

Furthermore, we analyzed the correlation between the cell numbers of TH neurons and the levels of phosphorylated tau or lipofuscin autofluorescence in SN TH neurons