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Moreover, GIP has been found to boost glucose uptake by improving insulin sensitivity in adipocytes (176, 177), while tirzepatide has been demonstrated to enhance insulin sensitivity and promote glucose disposal in white adipose tissue in Glp-1r-null mice (178), further supporting a direct effect of GIP on adipose tissues

The Road Ahead: Future Prospects of GLP-1 Agonists The future of GLP-1 agonists appears promising, with ongoing research aimed at enhancing their efficacy while minimizing side effects

That said, these numbers come from different studies with different populations and durations

They charge more in wealthy countries and less in developing economies

The result is a decrease in ectopic fat storagea hallmark of insulin resistance and NAFLD