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Chem Biol 15:234245 Wewer M, Bittker JA, Lewis TA, Shimada K, Yang WS, MacPherson L et al (2012) Development of small-molecule probes that selectively kill cells induced to express mutant RAS
ROS level elevation activates the detoxification and repair pathways
Typical Weekly Pattern During This Phase Weight loss: 0-0.5 pounds weekly average, with frequent plateau weeks Appetite: Remains suppressed compared to baseline but increased compared to weeks 8-28 Energy: Stable at levels established in weeks 25-36 Side effects: Essentially none
Microbial habitability of Europa sustained by radioactive sources
Because these medications affect different biological systems, they don't directly block or enhance each other's chemical activity
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