Kovacic P
In this 30-minute EU User Group Meeting talk, they walk through: Why a single tryptic digest leaves complex bispecifics under 75% covered The 9-enzyme combination (3 specific + 6 unspecific) they use to reach 100% Variant Analysis Coverage A side-by-side benchmark of six quantification strategies on a designed 126-variant spike-in dataset The Byologic report-tab setup for weighted quantification across digests and why it lands closest to truth If you're characterising bispecifics, knob-into-hole formats, or any complex multispecific this is the technique pack
If you hit a weight target that is acceptable to you and your labs have improved, you should not feel pressured or need to increase the dose in pursuit of a lower weight
The larger the volume, the finer the resolution
These community protocols vary widely
Cats could soon be offered Ozempic-style weight-loss jabs to help them 'live healthier, longer lives' (stock image) GLP-1 drugs work by mimicking a naturally occurring hormone called glucagon-like-peptide-1, which stimulates insulin production, limits digestion, and creates feelings of fullness