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Route of Administration How a peptide is delivered dramatically affects how long it stays in the body: Subcutaneous injection : slower absorption, longer duration Intramuscular injection : faster peak concentration, moderate duration Oral and intranasal peptides : often rapidly broken down, requiring protective technologies or higher doses For example, oral BPC-157 may work primarily through gut-localized pathways, while injectable versions may provide broader systemic benefits

The dead space problem Every syringe has "dead space," a small amount of liquid that remains in the needle hub after injection

Effect of recombinant human epidermal growth factor against cutaneous scar formation in murine full-thickness wound healing

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10.1155/2019/9084643 67 KraljT.KokotA.KasnikK.DrmicD.ZlatarM.SeiwerthS.et al (2017)

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