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In mammals, GST isoforms have cell specific distributions (for example, -GST in hepatocytes and -GST in the biliary tract of the human liver)

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Activated microglia serve a dual role during ischemia, releasing pro-inflammatory cytokines (such as TNF- and IL-1) that can aggravate ischemic injury, whilst promoting the release of anti-inflammatory cytokines (such as IL-10) to reduce ischemic injury [2]

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For instance, when toll-like receptor-2 knockout (TLR2 / ) mice were given S