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They are bigger and more organized than smaller peptides, allowing them to carry out special functions

doi: 10.1155/2016/8910396

Cell Mol

2022;13 doi: 10.3389/fendo.2022.1032199

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This review further summarized recent advances on research into the molecular mechanism of GH-IGF1 signaling pathway in these effects, expecting to specify the dual characters of GH-IGF1 signaling pathways in radiotherapy and post-radiotherapy repair of cancers, subsequently providing theoretical basis of their roles in increasing radiation sensitivity during cancer radiotherapy and repairing damage after radiotherapy