Both PAD and tTG are active in joints and the intestine, with the latter of these modification proteins being over expressed in the synovium of RA patients suggesting a possible role in disease pathogenesis (Lauzier et al
Its a workhorse: it helps convert the food you eat into usable cellular energy, drives red blood cell production , protects the myelin sheath that keeps nerves firing cleanly, and supports the synthesis of mood-regulating signals like serotonin and dopamine
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