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Synthetic small molecule SIRT1 activators Compared with natural products, synthetic SIRT1 activators offer several advantages, including defined molecular structures, high target selectivity, and stable pharmacokinetic profiles, making them a promising direction for the clinical application of SIRT1-targeted therapies

Sackmann, Force-induced growth of adhesion domains is controlled by receptor mobility

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The treatment also reshaped the gut microbiota, with correlation analyses indicating that specific bacterial genera associated with TMAO levels were also linked to inflammatory factors and barrier function, underscoring NSPTs role in modulating the oral-gut axis to improve systemic health (Huang et al., 2025b)

Actual stress, psychopathology and salivary cortisol levels in the irritable bowel syndrome (IBS)