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The other long-term concern is muscle loss (sarcopenia), which is not drug specific it accompanies any form of rapid weight reduction, and needs preventive measures like enhanced protein intake and strength training to be instituted from the beginning

Some GLP-1s also have been approved for sleep apnea and to reduce the risk of heart disease as well

Additionally, both peptide 14 and liraglutide were shown to similarly prevent a 1.5% increase in Hba1c relative to the vehicle over the course of 32 days in db/db mice [51]

From animal studies to human evidence, this conversation separates facts from assumptions so you can understand what is known, what is not, and what doctors want patients to be cautious about before considering it

Circulation 1983

Similarly, Doncheva et al