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To further support that ER knockdown induced ferroptosis, ER+ breast cancer cells were exposed to the ferroptosis inhibitor Ferrostatin-1

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Hippuric acid, a glycine conjugate involved in liver detoxification, showed a decrease post-seizure, likely indicating a depletion of glycine, which also functions as a neurotransmitter in inhibitory signalling in the central nervous system 33

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con una reduccin del riesgo atribuible del 12 al 68% de los casos (pre y post maniobra)