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Additionally, yes-associated protein (YAP) protein expression, a major determinant of cell fate and downstream of actin dynamics and the RhoA/ROCK, is inhibited under high-glucose conditions [30]

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Yue, J., Liu, J., Wang, T., Meng, T., Yang, R., Peng, C., Guan, S., Wang, Y., & Yan, D

However, the safety and efficacy of these combinations have not been extensively studied, and the decision to use multiple weight loss drugs should be made under close supervision by a qualified healthcare provider

559 When non-pharmacological measures are insufficient, pharmacological treatments may be considered

Torres RM, Souza MDS, Coelho ACC, de Mello LM, Souza-Machado C