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doi: 10.1097/EE9.0000000000000238 40 ShiLZhengJYanSLiYWangYLiuXet al

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(81) functionally investigated the role of thioredoxin redox proteins ( Txdnc2 and Txdnc3 ) in mice to show that these genes limited oxidative stress ( P 40 years of age compared with those younger than 40 years of age, although a significant relationship between DNA fragmentation and increased paternal age was observed