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To clarify the role of ferroptosis regulators in the progression of LN, we first obtained a total of 339 differentially expressed genes (DEGs) (241 upregulated and 98 downregulated genes) related to LN
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Glioma stem-like cells also upregulate hypoxia-inducible gene 2 (HIG-2) under low oxygen, leading to lipid accumulation and Wnt/-catenin activation via FZD10, which increases insulin-like growth factor binding protein 2 (IGFBP2) secretion and suppresses radioimmunogenicity 103
Multi-targeted therapeutic agents that impact both p53-dependent and independent checkpoints offer significant therapeutic potential, as these intersecting pathways ensure effective proliferation control while driving cancer cell death through apoptosis 46,47,48
Application of superoxide dismutase in medicine Dermatology and Aesthetic Medicine Superoxide dismutase can reduce free radical damage to skin cells - for example, reduce post-radiation fibrosis in breast cancer
