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High Purity: Typically 95%, confirmed through chromatographic and spectrometric methods

The DECLARE, CANVAS and EMPA-REG CV outcomes trials assessing the SGLT2 inhibitors dapagliflozin (Farxiga, AstraZeneca), canagliflozin (Invokana, Janssen) and empagliflozin (Jardiance, Boehringer Ingelheim/Eli Lilly), respectively, all showed CV and renal benefit in adults with type 2 diabetes with established CVD, DeFronzo said

The exact timeline depends on how each stage of the chart is tolerated and whether a provider extends any step along the way