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Additionally, the IGF-1/IGFBP-3 ratio, a common rough of free IGF-1 levels, is significantly decreased in obesity [216], however no IGF-1 bioactivity was estimated

This kind of peer-to-peer knowledge is especially valuable in a field where controlled trial data is limited

J Endocrinol 2010;204:23340

It also incorporates, when available, Ontario data and information provided by experts and applicants to Health Quality Ontario