Safety-wise, both drugs cause similar gastrointestinal side effects (nausea, vomiting, diarrhea), but tirzepatide showed fewer discontinuations due to these issues (2.7% vs
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This innovative compounding base may also benefit from mucoadhesive properties which increase the contact time of the drug in the sublingual space
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More serious but rare adverse events include pancreatitis, gallbladder events, and hypoglycemia (primarily in patients using insulin simultaneously)