In a hospital or clinic, if a medication order allows it, a pharmacist might choose bacteriostatic water to reconstitute a multi-dose vial of a drug so that it can be used for multiple patients/doses (as long as its safe for that drug and patient population)
They are a recurring reality, and compounding pharmacies exist to solve them for the patients caught in the middle
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For researchers comparing blend versus separate vials, the math is meaningfully close, with the blend earning its small premium through ratio consistency, documentation simplification (one batch, one COA), and single-reconstitution efficiency
For example, Gibbons et al