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The most commonly used classes of antidepressants include tricyclic antidepressants, selective serotonin reuptake inhibitors, serotonin and norepinephrine reuptake inhibitors, and norepinephrine and specific serotonin antidepressants

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Patients with 5 -reductase-2 deficiency syndrome have decreased circulating and prostatic DHT concentration due to attenuated 5 -reductase activity