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Cancer Causes Control 21 , 479483, (2010)

ME1 is a mitochondrial enzyme that metabolizes malate to pyruvate to generate NADPH

In some cases, they might even remain permanently

10.1007/5584_2019_381 Summary Keywords osteoarthritis, chondrocyte ferroptosis, synovial inflammation, regenerative therapy, meniscus degeneration Citation Qiu L, Alhaskawi A and Moqbel SAA (2026) Osteoarthritis: multitissue pathology, molecular mechanisms, clinical management, and emerging precision and regenerative therapies