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Proia et al

Today, during surgery, a strangulated loop of large bowel herniating through a left antero-lateral congenital diaphragmatic hernia was discovered, which was reduced and repaired with a Prolene mesh through thoracotomy

The Chemistry Behind the Rules of Thumb "Peptides cannot be taken orally." This rule is really about molecular weight, hydrogen-bonding capacity, and proteolytic susceptibility combined

Yap et al., 2016)

This pharmacokinetic profile enables weekly dosing while maintaining stable therapeutic levels throughout the dosing interval

Finally, if the serum cobalamin concentration at the time of reevaluation is subnormal [lower than normal], further work-up is required to definitively diagnose the underlying disease process and cobalamin supplementation should be continued weekly or bi-weekly