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A randomised controlled trial randomising 149 women with clomiphene-resistant PCOS (133 analysed) at a single Karachi centre, published in the Journal of Reproduction & Infertility , found that adding CoQ10 to clomiphene citrate raised ovulation rates from 19% to 70%, with women receiving the combination roughly six times more likely to conceive than those on clomiphene alone (adjusted OR 6.34, 95% CI 1.4527.71)
It is a precursor to glutathione, a powerful antioxidant in the body that protects cells from free radical damage
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For several other biologically relevant metals, thiol-bound forms were postulated to form, or actually highlighted by ex vivo in vitro experiments that were performed mainly on whole blood or in isolated red blood cells
doi: 10.3390/ijms21093289 55