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We connected the whole body model of acetaminophen metabolism to our previously constructed model of glutathione metabolism[9] so that we could study the depletion of GSH after APAP doses of various sizes (Figure6)

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Acetaminophen is metabolized in the liver and consumes glutathione, the bodys primary antioxidant

doi: 10.3389/fpsyg.2025.1498717, 51

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