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Examples of psychotropic medications that require slow, careful tapering are: benzodiazepines: antipsychotics: phenothiazines, such as fluphenazine or perphenazine thioxanthenes, such as thiothixene antidepressants: selective serotonin reuptake inhibitors (SSRIs), such as escitalopram (Lexapro) or fluoxetine (Prozac) monoamine oxidase inhibitors (MAOIs), such as phenelzine (Nardil) or selegiline (Emsam) serotonin-norepinephrine reuptake inhibitors (SNRIs), like duloxetine (Cymbalta) or venlafaxine (Effexor) Clinical guidelines stress that drugs prescribed for mental health conditions may require tapering

17 Obesity Obesity is a major contributing factor for CKD, explained in part by the observation that obesity predisposes individuals to diabetes and hypertension

Semaglutide (Wegovy, Ozempic, and Rybelsus) Semaglutide is in a category of prescription drugs called glucagon-like peptide-1 agonists, or GLP-1s, and they have upended the way obesity is treated

However, each dose increase can trigger a recurrence of nausea and digestive symptoms

In vitro sensitivity assays and clinical response to glucocorticoids in patients with inflammatory bowel disease

DiPeso L, Ji DX, Vance RE, Price JV (2017) Cell death and cell lysis are separable events during pyroptosis