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Some, such as semaglutide, have received FDA clearance to treat non-diabetic obesity and concomitant overweight

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In a retrospective cohort study of 16,827 patients in a single-center neuroophthalmology clinic, Hathaway et al found that semaglutide use was significantly associated with an increased incidence of NAION among patients with diabetes (HR = 4.28)

What is the pipeline for future medications for obesity

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An increase in IGF-1 in the circulation, in the liver and also in the muscle was observed in the Goat -/- mice, either as a result of the disordered GH pulse pattern, or because there was a failure of the elevated IGF-1 levels to feedback on GH release