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Of note, development of these cells required the presence of an intact microbiota and the activity of CD11c(+) dendritic cells, along with innate immune factors operating through Toll-like receptor-2

Conclusions In addition to the conventional mechanism of desensitization, which occurs on the plasma membrane and in the cytosol, this study provides a new insight that another desensitization pathway in which nuclear trafficking plays a critical role is operating

Research demonstrates improved muscle repair following injury, enhanced recovery from exercise, and protection against muscle wasting conditions including Duchenne muscular dystrophy

Int J Cancer 2009

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Emerging approaches, such as antioxidants, NMDA receptor modulators, and cognitive rehabilitation, show promise but require further validation