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[DOI] [PMC free article] [PubMed] [Google Scholar] Shi JF, Li YK, Ren K, Xie YJ, Yin WD, Mo ZC, 2018

A Swedish study following over 3,000 MS patients for more than a decade found obesity was associated with a 43% higher risk of reaching significant disability milestones

Li K, Zhang J, Qin Y, Wei Y-X

Oral Secretagogues: Development continues on oral growth hormone secretagogues like LUM-201 (Ibutamoren/MK-677 related compound) for pediatric GH deficiency, offering pulsatile GH secretion through oral administration

Federal officials recently announced plans to make these medications more accessible and affordable, including to people who have Medicare, which currently does not cover medications strictly for weight loss

I generally do not advise patients to discontinue abruptly, not only because of the increased risk of rebound, but also because it can cause uncontrolled sugar spikes initially, Dr