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Weight should be monitored at each clinical encounter, typically monthly during active dose titration and quarterly once maintenance dose is achieved

While higher doses of semaglutide generally provide greater appetite suppression, even the maximum dose (2.4mg for Wegovy) won't completely eliminate hunger

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Standard escalation approach The typical retatrutide dose escalation starts low and increases over several weeks

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Some preclinical data suggests this could be beneficial in conditions characterized by chronic low-grade inflammation, which includes most metabolic diseases