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Louis Aronne, a principal investigator on the clinical trial involving Zepbound and Wegovy, told ABC News that the success of drugs using tirzepatide is likely because the ingredient targets two hormones instead of one

One important caveat: biotin in high doses interferes with common laboratory tests, including thyroid panels, troponin (cardiac markers), and hormone levels

Rybelsus (semaglutide) is a prescription medicine used to treat type 2 diabetes in adults across the UK

"Preserved incretin activity of glucagon-like peptide 1 [7-36 amide] but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus." Journal of Clinical Investigation , 91(1), 301-307

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