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Source: Piaopiao, L et al JAMA Network Open October 31, 2025

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So there was some type of maintained benefit in certain cases." Do weight loss drugs become less effective over time

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These drugs have been around for over a decade now, and we can go and look into the epidemiologic evidence and see: these are the people with diabetes who took these drugs, and these are people with diabetes who didnt

Effect of GLP-1 agonists on testosterone levels: a systematic review and meta-analysis