It is heterogeneous in every aspect, such as the relation between the presence of plaques and tangles of A and Tau in the brain, clinical symptoms, and genetic background that causes memory loss, language problems, and impulsive or unpredictable behavior
Potential limitations of both studies include the use of a single dose rather than multiple doses of cagrilintide and the use of doses (0.6 mg in the renal impairment study and 0.9 mg in the hepatic impairment study) lower than the 2.4 mg dose being evaluated in clinical development
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