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The article's comparison table puts short-acting injectables at 5 to 7 days to steady state, oral formulations at 2 to 4 weeks, long-acting weekly injectables at 4 to 5 weeks to full effect, and dual GLP-1 and GIP agonists at 4 to 6 weeks

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* Subcutaneous Injection Sites Learn more about the differences of subcutaneous vs intramuscular injections.

Regarding hunger cues, it can also act on the central nervous system to further suppress appetite and increase satiety signals

(2007) 21:633vi