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This is often called a loading dose phase, and its purpose is to quickly raise the B12 levels in your body and help you start feeling better

Journal of the American Academy of Dermatology International

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J.SchweonS

Cytokine (2015) 76(2):52736

The enhanced cocktails, CILy (CHIR+IDE1+Ly) and CIP (CHIR+IDE1+PD), significantly increased the expression of DE markers SOX17 and FOXA2, with CIP showing the highest efficiency, comparable to the traditional CA method