Tired all the time has a lot of causes, and one of them is simple, common, and very fixable: low B12. It's worth ruling out before you write the exhaustion off as just life
I think the other important part that you were just talking about with the blood flow is that blood flow has oxygen
Additionally, acteoside, a major active compound, has been reported to alleviate renal fibrosis and glycolipid metabolic disturbances by reducing oxidative stress and inflammation in -cells, modulating the unfolded protein response, improving mitochondrial dynamics, and enhancing -cell function and insulin secretion (69)
Nicotinamide N-methyltransferase: a novel therapeutic target
Heightened regulatory focus on label accuracy, banned-substance compliance, and substantiated efficacy claims increases operational complexity for brands
JAMA 333 , 113114 (2025)