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134 In cancer cells, OXPHOS increases reactive oxygen species (ROS) production and leads to oxidative stress, activation of p53 signaling and DNA damage, particularly when combined with chemotherapy or other cancer therapies

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Regulation of circadian clocks by redox homeostasis

Under sulfur rich conditions, MetR was demonstrated to be uniformly distributed throughout the cytoplasm, however, under sulfur-depleted conditions, MetR localized strongly to the nucleus