In Parkinsons disease, there becomes an issue with oxidative damage in the brain as well as lower levels of glutathione
They also measure the glutathione redox potential rather than absolute GSH concentration, which is an important distinction researchers must account for when interpreting results
Varkaris A, Gaur S, Parikh NU, Song JH, Dayyani F, Jin JK, et al
Common mutation in methylenetetrahydrofolate reductase
GSSG in the samples was reduced with tris(2-carboxyethyl)phosphine (TCP) to GSH, and then derivatized with ABD-F to obtain the total concentration of thiols ([GSSG] = [GSH] total [GSH, prior to reduction with TCP])
carbonic anhydrase inhibitors promote stone formation by reducing urinary citrate excretion and by increasing urinary pH