incretin and glp-1 The system: glucagon-like peptide-1 receptor agonists dipeptidyl peptidase-4 inhibitors in type 2 diabetes Representation of the incretin effect

The Hypothalamus: This area of the brain is the master control centre for appetite and energy balance

2017;96(14):e6558

Adequate fluid intake supports digestion and helps offset common side effects like constipation

At the end of the study, the women who received the GLP-1 agonist had lost an average of 4.9 kg (10.8 lbs) and had significant improvements in insulin resistance, fasting glucose, and cholesterol levels

While rare, more serious conditions like pancreatitis and gallbladder-related issues have also been reported

GLP-1 and GIP receptor activation produces gastrointestinal effects (nausea, reduced appetite) that are dose-dependent