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In the dynamic simulation of GSH_a, the conformation exhibiting a hydrogen bond between N259 and the ligand occurs 100% of the time, while E255 appears over 95% (Table 3)

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This leads to several effects, like slowing down gastric emptying, i.e

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It is highly effective in providing protection against membrane lipid peroxidation by reacting with lipid peroxyl radicals (Yu, 1994)