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Eli Lilly says its oral GLP-1 drug, orforglipron, can be taken once a day at any time without food or water restrictions

In this context, GLP-1R agonists show remarkable potential as an emerging therapeutic agent.GLP-1R agonists reduce body weight, lower blood pressure, and improve lipid levels, as well as exerting anti-inflammatory and antioxidant effects by directly acting on GLP-1R in the heart and blood vessels, thereby reducing the risk of atherosclerotic thrombotic events (Solini et al., 2023)

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the prepared semaglutide has high purity and industrial production is facilitated

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