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Why GLP-1 medications cause constipation in the first place Understanding the mechanism matters

Some need longer depending on side effects and weight loss progress

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121,134 GIP, another insulin secretion agonist, helps release insulin, particularly after eating, enhancing the effects of GLP-1 and thereby improving the overall therapeutic efficacy of the drug

GLP-1 is an endocrine hormone secreted by enteroendocrine L-cells located in the distal jejunum, ileum and colon that express the glucagon gene and produce proglucagon (Lee et al., 1990)

Natalie Azar said on TODAY